SR9009 (Stenabolic)

SR9009 is a synthetic Rev-Erb ligand, which is taken orally.

Stenabolic has the ability to alter the activity of the skeletal muscle mitochondria, that is, it boosts the metabolic activity.

SR binds to this protein and makes it more active. As a result, the user will experience a lot of positive effects, such as increased fat loss, enhanced endurance, and many other health benefits.

By stimulating the Rev-Erb protein, SR9009 has the ability to greatly influence a lot of regulatory mechanisms in the human body. It can affect the circadian rhythms, lipid and glucose metabolism, fat-storing cells, as well as macrophages. In this way, Stenabolic will allow the user to lose fat and drastically increase endurance, both of which are very desirable effects for an athlete.

SR9009 opens to an athlete amazing endurance and strength, fat loss, muscle growth, improved cholesterol and blood sugar levels, and an increased metabolism.

Stenabolic should be dosed at 20-30 mg per day and adjusted up or down by 10mg depending on user preference. The typical cycle length is 6-8 weeks. SR9009 can be stacked with Cardarine for a double dose of endurance power.

which is currently under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice. Treated mice become lean, develop larger muscles and can run much longer distances simply by taking SR9009, which mimics the effects of aerobic exercise.

has great promise in increased exercise capacity and endurance. This compound acts as an agonist of Rev-erbα. SR9009 binds to one of the body’s natural molecules called Rev-erbα, which influences lipid and glucose metabolism in the liver, the production of fat-storing cells and the response of macrophages (cells that remove dying or dead cells) during inflammation. Current studies show activation of Rev-erbα with SR9009 led to increased metabolic activity in skeletal muscle in both culture and in mice. The treated mice had a 50 percent increase in running capacity, measured by both time and distance.
SR9009 latches onto Rev-erbα — which plays a role in regulating the body’s circadian rhythm and metabolism — resulting in a pronounced metabolic boost in test subjects.

Effect

Stenabolic should be dosed at 20-30 milligrams (mg) per day and adjusted up or down by 10mg depending on user preference. Regarding the cycle duration, the typical cycle length is 6-8 weeks, and it would be wise to stack SR9009 with Cardarine (GW-501516) for a double dose of endurance power.


There is a big inconvenience with Stenabolic when compared to Cardarine, SR9009 does not have a long half life, so it is must be dosed 3-4 times per day. However, some forum members have had good success dosing it at 2-3 times per day.

Without the addition of SR9009, the body’s metabolism fluctuates, constantly peaking and dipping according to activity. has the effect of making the body act like it’s exercising all of the time, by increasing the basal metabolic rate. Even in periods of no activity at all, the metabolic rate is raised by 5%. All excess calories are burned up and not stored as fat, and glucose is metabolized more effectively. And unlike certain other compounds, doesn’t act as an appetite suppressant. All of these actions reduce the amount of fat and stop more from accumulating. But not only does SR9009 prevent fat from being stored in the body, it even creates improved musculature, just like following exercise. Endurance increases too, allowing longer and harder training, which also contributes to better muscle mass and lower fat levels.

Side effect

Steroids can lower HDL cholesterol, and raise LDL cholesterol. HDL (high density lipoprotein, commonly referred to as “good cholesterol”) helps to protect the arteries by bringing unused cholesterol to the liver where it is broken down. LDL on the other hand has the opposite effect. Some steroids can therefore cause high cholesterol levels with low HDL and high LDL. Some steroids are, of course, very mild on blood lipids, while others are notably harsh. In both cases, however, it is likely that a return to within normal.

The development of gynecomastia or feminization of the breast tissue in males is possible with anabolic steroids. This is due to an excess of estrogen being present in the body, through a process known as “aromatization” whereby androgens like testosterone are converted to estrogen. This excess estrogen then finds its way to the receptors in breast tissue and binds to them. This results in the possibility of female-like breast tissue, which must sometimes be removed by surgery. Most athletes experience itchiness of the nipples, followed by pain. Since this develops over several days, usually, the athlete has more than enough time to discontinue the use of the compounds he´s taking, or to attempt to counteract the breast tissue development while remaining on the cycle. The two most common ways to counteract gynecomastia are the use an anti-estrogen like Nolvadex or Clomiphene Citrate (best taken post-cycle) or Letrozole, a very strong Aromatase Inhibitor (AI)/anti-estrogenic compound is employed during cycle to effectively starve the growth of nourishing estrogen.

The initiation and progression of breast development involves a variety of pituitary (and ovarian, in women) hormones, as well as various local mediators. As you can see in the following chart, testosterone has the ability to aromatize (convert to estrogen), and eventually become part of the cascade of hormones that contribute to the development of breast tissue.